A referendum on Welsh independence from the United Kingdom (UK) has been proposed by pro-independence supporters, including independence campaign group YesCymru, pro-independence political party Plaid Cymru and other groups and individuals. These follow similar calls for a proposed second Scottish independence referendum. Pro-independence party Plaid Cymru has pledged to hold a referendum should they win a majority of seats in the Senedd.

Welsh independence is the political movement advocating for Wales to become a sovereign state, independent from the United Kingdom.