Proserpine is a French-language opera by the Italian composer Giovanni Paisiello. It takes the form of a tragédie lyrique in three acts. The libretto, by Nicolas-François Guillard, is a reworking of Philippe Quinault's Proserpine. Paisiello's opera was first performed on 28 March 1803 at the Paris Opéra.

Giovanni Paisiello was an Italian composer of the Classical era, and was the most popular opera composer of the late 1700s. His operatic style influenced Mozart and Rossini.