The province of Campobasso is a province in the Molise region of Italy. Its capital is the city of Campobasso. It covers an area of c. 2,941 square kilometres (1,136 sq mi) and has a total population of 223,871 (2017). There are 84 comuni in the province.

Molise is a region of Southern Italy. Until 1963, it formed part of the region of Abruzzi e Molise together with Abruzzo. The split, which did not become effective until 1970, makes Molise the newest region in Italy. Covering 4,438 square kilometres (1,714 sq mi), it is the second smallest region in the country, after the Aosta Valley, and has a population of 313,348.