The Ptolemaic dynasty was a Macedonian Greek royal house which ruled the Ptolemaic Kingdom in Ancient Egypt during the Hellenistic period. Reigning for 275 years, the Ptolemaic was the longest and last dynasty of ancient Egypt from 305 BC until its incorporation into the Roman Republic in 30 BC.

Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. By analogy, the term is used in human reproduction, but more commonly refers to the genetic disorders and other consequences that may arise from expression of deleterious recessive traits resulting from incestuous sexual relationships and consanguinity. Animals avoid incest only rarely.