Publication bias
Videos
In published academic research, publication bias occurs when the outcome of an experiment or research study biases the decision to publish or otherwise distribute it. Publishing only results that show
Conceptual illustration of how publication bias affects effect estimates in a meta-analysis. When negative effects are not published, the overall effect estimate tends to be inflated. From Nilsonne (2023).
Replication crisis
Videos
The replication crisis, also known as the reproducibility or replicability crisis, refers to widespread failures to reproduce published scientific results. Because the reproducibility of empirical res
Publication bias
…Proteus phenomenon – Phenomenon in scientific publishing Replication crisis – Observed inability to reproduce scientific studies Selection bias – Bias in a statistical analysis due to non-random selection…
Results from The Reproducibility Project: Cancer Biology suggest most studies of the cancer research sector may not be replicable.
"The overall process of testing the reproducibility and robustness of the cancer biology literature by robot. First, text mining is used to extract statements about the effect of drugs on gene expression in breast cancer. Then two different teams semi-automatically tested these statements using two different protocols, and two different cell lines (MCF7 and MDA-MB-231) using the laboratory automation system Eve."
Ioannidis (2005): "Why Most Published Research Findings Are False".