Purinergic signalling
Videos
Purinergic signalling is a form of extracellular signalling mediated by purine nucleotides and nucleosides such as adenosine and ATP. It involves the activation of purinergic receptors in the cell and
Exogenously applied ATP stimulates the closure of the Venus flytrap
Homology modeling of the P2RX2 receptor in the open channel state
Microglial activation in the CNS via purinergic signalling
Clopidogrel (Plavix), an inhibitor of the P2Y12 receptor, was formerly the second best-selling drug in the world
Actin
Videos
Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where i
Fluorescence micrograph showing F-actin (in green) in rat fibroblasts
Structure of the C-terminal subdomain of villin, a protein capable of splitting microfilaments
Giant nemaline rods produced by the transfection of a DNA sequence of ACTA1, which is the carrier of a mutation responsible for nemaline myopathy
Position of seven mutations relevant to the various actinopathies related to ACTA1