Pynes House is a Grade II* listed Queen Anne style country house built by Hugh Stafford between around 1700 and 1725, situated in the parish of Upton Pyne, Devon, 3 miles northwest of Exeter. It was the manor house for the Manor of Upton Pyne, which included the village of Upton Pyne.

Stafford Henry Northcote, 1st Earl of Iddesleigh, known as Sir Stafford Northcote, 8th Baronet from 1851 to 1885, was a British Conservative politician. He served as Chancellor of the Exchequer between 1874 and 1880 and as Foreign Secretary between 1885 and 1886