Quantico is a town in Prince William County, Virginia, United States. The population was 480 at the 2010 census. Quantico is approximately 35 miles southwest of Washington, D.C., bordered by the Potomac River to the east and the Quantico Creek to the north. The word Quantico is a corruption of the name of a Doeg village recorded by English colonists as Pamacocack.

Virginia Railway Express (VRE) is a commuter rail service that connects outlying small cities of Northern Virginia to Union Station in Washington, D.C. It operates two lines which run during weekday rush hour only: the Fredericksburg Line from Spotsylvania, Virginia, and the Manassas Line from Broad Run station in Bristow, Virginia. In 2023, the system had a ridership of 1,537,000, or about 5,900 per weekday as of the fourth quarter of 2023.