A quark is a type of elementary particle and a fundamental constituent of matter. Quarks combine to form composite particles called hadrons, the most stable of which are protons and neutrons, the components of atomic nuclei. All commonly observable matter is composed of up quarks, down quarks and electrons. Owing to a phenomenon known as color confinement, quarks are never found in isolation; they can be found only within hadrons, which include baryons and mesons, or in quark–gluon plasmas. For this reason, much of what is known about quarks has been drawn from observations of hadrons.

Murray Gell-Mann was an American theoretical physicist who played a preeminent role in the development of the theory of elementary particles. Gell-Mann introduced the concept of quarks as the fundamental building blocks of the strongly interacting particles, and the renormalization group as a foundational element of quantum field theory and statistical mechanics. He played key roles in developing the concept of chirality in the theory of the weak interactions and spontaneous chiral symmetry breaking in the strong interactions, which controls the physics of the light mesons. In the 1970s he was a co-inventor of quantum chromodynamics (QCD) which explains the confinement of quarks in mesons and baryons and forms a large part of the Standard Model of elementary particles and forces.