Quincy Regional Airport is a city-owned airport 12 miles east of Quincy, a city in Adams County, Illinois, United States. It is used for general aviation but also sees Southern Airways Express flights to Chicago's O'Hare International Airport and St. Louis Lambert International Airport, a service which is subsidized by the federal government's Essential Air Service program at a cost of $1,956,856. The Federal Aviation Administration (FAA) National Plan of Integrated Airport Systems for 2023–2027 categorized it as a national non-primary commercial service facility.

Quincy is a city in and the county seat of Adams County, Illinois, United States, located on the Mississippi River. The population was 39,463 as of the 2020 census, down from 40,633 in 2010. The Quincy micropolitan area had 114,649 residents.