Rüstem Pasha was an Ottoman statesman who served as Grand Vizier to Sultan Süleyman the Magnificent. Rüstem Pasha is also known as Damat Rüstem Pasha as a result of his marriage to the sultan's daughter, Mihrimah Sultan, in 1539. He is regarded as one of the most influential and successful grand viziers of the Ottoman Empire.

Mihrimah Sultan was an Ottoman princess, the daughter of Ottoman Sultan Süleyman the Magnificent and his wife, Hürrem Sultan. She was the most powerful imperial princess in Ottoman history according to historian Mustafa Selaniki who described her as the greatest and most respected princess and a prominent figure in the so-called Sultanate of Women. In Europe she was known as Sultana Cameria, while in Constantinople she was known as Büyük Sultan.