The R4600, code-named "Orion", is a microprocessor developed by Quantum Effect Design (QED) that implemented the MIPS III instruction set architecture (ISA). As QED was a design firm that did not fabricate or sell their designs, the R4600 was first licensed to Integrated Device Technology (IDT), and later to Toshiba and then NKK. These companies fabricated the microprocessor and marketed it. The R4600 was designed as a low-end workstation or high-end embedded microprocessor. Users included Silicon Graphics, Inc. (SGI) for their Indy workstation and DeskStation Technology for their Windows NT workstations. The R4600 was instrumental in making the Indy successful by providing good integer performance at a competitive price. In embedded systems, prominent users included Cisco Systems in their network routers and Canon in their printers.

Quantum Effect Devices, Inc. (QED), was a microprocessor design company incorporated in 1991 as Quantum Effect Design. It was based in Palo Alto, California.