The RFU Knockout Cup was an English rugby union competition open to any member of the Rugby Football Union. First contested in 1971, it was the premier competition in English club rugby before the establishment of the English league structure in 1987.

London Irish RFC was a professional rugby union club, currently in administration, which competed in the Premiership, the top division of English rugby union. The club had also competed in the Anglo-Welsh Cup, the European Champions Cup and European Challenge Cup. While playing in the Championship in 2016–17 and 2018–19, it also played in the British and Irish Cup and RFU Championship Cup. The club played home games at the Madejski Stadium in Reading, Berkshire for twenty years, before moving for the 2020–21 season to the Gtech Community Stadium in Brentford, West London.