Radial glial cell
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Radial glial cells, or radial glial progenitor cells, are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineag
G-CSF receptor expression clearly delineates cells of radial glia in the embryonic murine brain. From Kirsch et al., 2008.
Slcla3 in Bergmann Glia
Micrograph showing Bergmann gliosis. H&E stain.
Stages of neuronal development in the fetal cerebral cortex from radial glial cells
Ventricular zone
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In vertebrates, the ventricular zone is a transient embryonic layer of tissue containing neural stem cells, principally radial glial cells, of the central nervous system. The VZ is so named because it
Radial glial cell
…cortex. RGPs also produce certain lineages of glia, including astrocytes and oligodendrocytes. Their cell bodies (somata) reside in the embryonic ventricular zone, which lies next to the developing ventricular system. During development, newborn neurons use radial glia as scaffolds, traveling along the radial…
The VZ and SVZ are indicated by immunohistochemical labelling of Sox2 and Tbr2 gene expression in the embryonic mouse forebrain at embryonic day 13.5. The dorsal telencephalon becomes the cerebral cortex, and contains the Tbr2-labeled cells. CP, cortical plate; LV, lateral ventricle; MGE, medial ganglionic eminence