Ramón Villeda Morales International Airport, also known as La Mesa International Airport, is located 11 kilometres (7 mi) southeast of the city of San Pedro Sula, in the Cortés Department of Honduras.

San Pedro Sula is the capital of Cortés Department, Honduras. It is located in the northwest corner of the country in the Sula Valley, about 50 kilometers south of Puerto Cortés on the Caribbean Sea. With a population of 701,200 in the central urban area and a population of 1,445,598 in its metropolitan area in 2023, it is the nation's primary industrial center and second largest city after the capital Tegucigalpa, and the largest city in Central America that is not a capital city.