Ramona and Beezus is a 2010 American comedy-drama film based on the Ramona series of novels written by Beverly Cleary. It was directed by Elizabeth Allen, co-produced by Dune Entertainment, Di Novi Pictures, and Walden Media, written by Laurie Craig and Nick Pustay, and produced by Denise Di Novi and Alison Greenspan with music by Mark Mothersbaugh. The film stars Joey King and Selena Gomez. Though the film's title is derived from Beezus and Ramona, the first of Cleary's Ramona books, the plot is mostly based on the sequels Ramona Forever and Ramona's World.

The Ramona books are a series of eight humorous children's novels by Beverly Cleary that center on Ramona Quimby, her family and friends. The first book, Beezus and Ramona, appeared in 1955. The final book, Ramona's World, was published in 1999. Two books in the series were named Newbery Honor books, Ramona and Her Father and Ramona Quimby, Age 8. Ramona and Her Mother received the National Book Award. Sometimes known as the Beezus and Ramona series, as of 2012, the books were being marketed by HarperCollins as "The Complete Ramona Collection".