Rancho Camulos, now known as Rancho Camulos Museum, is a ranch located in the Santa Clara River Valley 2.2 miles (3.5 km) east of Piru, California and just north of the Santa Clara River, in Ventura County, California. It was the home of Ygnacio del Valle, a Californio alcalde of the Pueblo de Los Angeles in the 19th century and later elected member of the California State Assembly. The ranch was known as the Home of Ramona because it was widely believed to have been the setting of the popular 1884 novel Ramona by Helen Hunt Jackson. The novel helped to raise awareness about the Californio lifestyle and romanticized "the mission and rancho era of California history."

The Santa Clara River Valley is a rural, mainly agricultural, valley in Ventura County, California that has been given the moniker Heritage Valley by the namesake tourism bureau. The valley includes the communities of Santa Paula, Fillmore, Piru and the national historic landmark of Rancho Camulos. Named for the Santa Clara River, which winds through the valley before emptying into the Pacific Ocean between the cities of Ventura and Oxnard, the tourist bureau describes it as ".... Southern California's last pristine agricultural valley nestled along the banks of the free-flowing Santa Clara River."