Reggie Lee Nelson is an American former professional football player who was a safety in the National Football League (NFL). He played college football for the Florida Gators, winning a national championship and earning consensus All-American honors. He was selected by the Jacksonville Jaguars in the first round of the 2007 NFL draft and also played for the Cincinnati Bengals and Oakland Raiders.

The 2007 NFL draft was the 72nd annual meeting of National Football League franchises to select newly eligible American football players. It took place at Radio City Music Hall in New York City, New York, on April 28 and April 29, 2007. The draft was televised for the 28th consecutive year on ESPN and ESPN2. The NFL Network also broadcast coverage of the event, its second year doing so. There were 255 draft selections: 223 regular selections and 32 compensatory selections. A supplemental draft was also held after the regular draft and before the regular season. This was the first draft presided over by new NFL Commissioner Roger Goodell.