The Regionalist Party of Cantabria is the second oldest political party in the Spanish Autonomous Community of Cantabria. The PRC originated in the Association in Defense of the Interests of Cantabria (ADIC), founded on 14 May 1976, with the objective of promoting Cantabrian autonomy.

Cantabria is an autonomous community and province in northern Spain with Santander as its capital city. It is called a comunidad histórica, a historic community, in its current Statute of Autonomy. It is bordered on the east by the Basque autonomous community, on the south by Castile and León, on the west by the Principality of Asturias, and on the north by the Cantabrian Sea, which forms part of the Bay of Biscay.