Remote control animals are animals that are controlled remotely by humans. Some applications require electrodes to be implanted in the animal's nervous system connected to a receiver which is usually carried on the animal's back. The animals are controlled by the use of radio signals. The electrodes do not move the animal directly, as if controlling a robot; rather, they signal a direction or action desired by the human operator and then stimulate the animal's reward centres if the animal complies. These are sometimes called bio-robots or robo-animals. They can be considered to be cyborgs as they combine electronic devices with an organic life form and hence are sometimes also called cyborg-animals or cyborg-insects.

Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain – usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g., in vision. Other brain implants are used in animal experiments simply to record brain activity for scientific reasons. Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain–computer interfaces.