Rex Reason was an American actor best known for his role in This Island Earth (1955). He was the elder brother of actor Rhodes Reason.

This Island Earth is a 1955 American science fiction film produced by William Alland, directed by Joseph M. Newman and Jack Arnold, and starring Jeff Morrow, Faith Domergue and Rex Reason. It is based on the 1952 novel of the same name by Raymond F. Jones. The film, distributed by Universal-International, was released in 1955 on a double feature with Abbott and Costello Meet the Mummy.