The Richmond Professional Institute (RPI) was an educational institution established in 1917 which merged with the Medical College of Virginia to form Virginia Commonwealth University. RPI was located on what is now known as the Monroe Park Campus of VCU. The entire history of RPI can be found in "A History of the Richmond Professional Institute" written by Dr. Henry H. Hibbs Jr. From 1925, it was part of the College of William & Mary and, later, The Colleges of William & Mary.

Virginia Commonwealth University (VCU) is a public research university in Richmond, Virginia. VCU was founded in 1838 as the medical department of Hampden–Sydney College, becoming the Medical College of Virginia in 1854. In 1968, the Virginia General Assembly merged MCV with the Richmond Professional Institute, founded in 1917, to create Virginia Commonwealth University. In 2022, more than 28,000 students pursued 217 degree and certificate programs through VCU's 11 schools and three colleges. The VCU Health System supports health care education, research, and patient care. It was the only school in the South to have graduated a class every year during the Civil War.