Rifle is a home rule municipality in, and the most populous community of, Garfield County, Colorado, United States. The population was 10,437 at the 2020 census. Rifle is a regional center of the cattle ranching industry located along Interstate 70 and the Colorado River just east of the Roan Plateau, which dominates the western skyline of the town. The town was founded in 1882 by Abram Maxfield, and was incorporated in 1905 along Rifle Creek, near its mouth on the Colorado. The community takes its name from the creek.

Interstate 70 (I-70) is a transcontinental Interstate Highway in the United States, stretching from Cove Fort, Utah, to Baltimore, Maryland. In Colorado, the highway traverses an east–west route across the center of the state. In western Colorado, the highway connects the metropolitan areas of Grand Junction and Denver via a route through the Rocky Mountains. In eastern Colorado, the highway crosses the Great Plains, connecting Denver with metropolitan areas in Kansas and Missouri. Bicycles and other non-motorized vehicles, normally prohibited on Interstate Highways, are allowed on those stretches of I-70 in the Rockies where no other through route exists.