The River Ancholme is a river in Lincolnshire, England, and a tributary of the Humber. It rises at Ancholme Head, a spring just north of the village of Ingham and immediately west of the Roman Road, Ermine Street. It flows east and then north to Bishopbridge west of Market Rasen, where it is joined by the Rase. North of there it flows through the market town of Brigg before draining into the Humber at South Ferriby. It drains a large part of northern Lincolnshire between the Trent and the North Sea.

The Humber is a large tidal estuary on the east coast of Northern England. It is formed at Trent Falls, Faxfleet, by the confluence of the tidal rivers Ouse and Trent. From there to the North Sea, it forms part of the boundary between the East Riding of Yorkshire on the north bank and North Lincolnshire on the south bank. Although the Humber is an estuary from the point at which it is formed, many maps show it as the River Humber.