Rochester General Hospital, an affiliate hospital of Rochester Regional Health, is a 528-bed tertiary care hospital, located in Rochester, New York. Rochester General Hospital has been serving the residents of the Rochester Region and beyond since 1847. Rochester General Hospital offers primary medical care and a broad range of specialties. Rochester General Hospital's medical staff includes over 1,000 primary care physicians and specialists, many of whom have offices at the hospital and throughout the community.

Rochester Regional Health in Rochester, New York is an integrated health system that was formed in 2014 by the joining of Rochester General and Unity Health systems, and acquiring of St. Lawrence Health System in 2021.