Mexican rock music, often referred to in Mexico as rock nacional, originated in the 1950s. Standards by The Beatles, Elvis Presley, The Everly Brothers, Nancy Sinatra, and Chuck Berry were soon covered by bands such as Los Apson, Los Teen Tops, Los Twisters, Los Hitters, Los Nómadas, Los Rockets, Los Rebeldes del Rock, Los Locos del Ritmo, Los Crazy Boys, and Javier Bátiz, which later led to original compositions, often in English. The group "Los Nómadas" was the first racially integrated band of the 1950s. Their lead guitarist, Bill Aken, wrote most of their original material, including the raucous Donde-Donde, and co-wrote the material for their Sounds Of The Barrio album, which is still being sold. Their 1954 recording of She's My Babe was the first top 40 R&B recording by a Latino band. In the southwestern United States, Spanish guitar rhythms and Mexican musical influences may have inspired some of the music of American musicians Ritchie Valens, Danny Flores, Sam the Sham, Roy Orbison, and later, Herb Alpert. Initially, the public exhibited only moderate interest in them, because the media attention was focused on La Ola Inglesa.

Chicano rock, also called chicano fusion, is rock music performed by Mexican American (Chicano) groups or music with themes derived from Chicano culture. Chicano Rock, to a great extent, does not refer to any single style or approach. Some of these groups do not sing in Spanish at all, or use many specific Latin instruments or sounds. The subgenre is defined by the ethnicity of its performers, and as a result covers a wide range of approaches.