Roma Ostiense is a railway station in Piazza dei Partigiani serving the Ostiense district of Rome, Italy, a short distance from the Porta San Paolo. It is run by the Rete Ferroviaria Italiana arm of the Ferrovie dello Stato Italiane group and the commuter rail lines FL1, FL3, and FL5 run through the station. It is linked with the Piramide Metro B station and the Roma Porta San Paolo station on the Rome-Lido railway line.

The FL1 is a regional rail route forming part of the Lazio regional railways network, which is operated by Trenitalia, and converges on the city of Rome, Italy.