The Archdiocese of Aix-en-Provence and Arles is a Latin Church ecclesiastical territory or archdiocese of the Catholic Church in France. The archepiscopal see is located in the city of Aix-en-Provence. The diocese comprises the department of Bouches-du-Rhône, in the Region of Provence-Alpes-Côte d'Azur. It is currently a suffragan of the Archdiocese of Marseilles and consequently the archbishop no longer wears the pallium.

Pierre Desprès (1288–1361) was a French Cardinal during the period of the Avignon Papacy.