The Diocese of Owensboro is a Latin Church ecclesiastical territory, or diocese, of the Catholic Church in western Kentucky in the United States. As of 2020, the diocese contained of 78 parises and two Newman Centers in 32 counties. The Diocese of Owensboro is a suffragan diocese in the ecclesiastical province of the metropolitan Archdiocese of Louisville.

The Archdiocese of Louisville is a Latin Church ecclesiastical territory, or archdiocese, of the Catholic Church in central Kentucky in the United States. The cathedral church of the archdiocese is the Cathedral of the Assumption in Louisville, Kentucky. The archdiocese is the seat of the metropolitan see of the Province of Louisville, which encompasses the states of Kentucky and Tennessee. The archdiocese is the second-oldest diocese west of the Appalachian Mountains, after the Archdiocese of New Orleans. As of 2023, the archbishop of Louisville is Shelton Fabre.