The Romanus House is a historic building in Leipzig, Germany, located in the borough Mitte, on the corner of Brühl and Katharinenstrasse. The city palace, built between 1701 and 1704, is one of the main works of Leipzig Baroque architecture influenced by Dresden. Previously used as a bourgeois residence building, it now serves as a commercial building. It is under heritage protection.

Leipzig-Mitte is one of ten boroughs (Stadtbezirke) of Leipzig, located in the center of the city. It includes numerous architectural monuments. Most of them are located in the subdivision "Zentrum", which is sited inside the Inner City Ring Road and the Promenadenring:the Opera, the Europahaus, the Gewandhaus, the City-Hochhaus at the Augustusplatz, the Wintergartenhochhaus, the St. Thomas Church, the St. Nicholas Church, the New Town Hall, the Old Town Hall at the Markt square, the Leipzig University.