Rosebush is a village in Isabella County in the U.S. state of Michigan. The population was 353 at the 2020 census. The village is within Isabella Township, and is also entirely within the Isabella Indian Reservation, home to the federally-recognized Saginaw Chippewa Tribal Nation.

Isabella County is a county located in the U.S. state of Michigan. As of the 2020 Census, the population was 64,394. Its county seat is Mount Pleasant. The area was known as Ojibiway Besse, meaning "the place of the Ojibwa". Isabella County contains the Isabella Indian Reservation, on which members of the Saginaw Chippewa Tribal Nation live.