The Rossano Gospels, designated by 042 or Σ, ε 18 (Soden), held at the cathedral of Rossano in Italy, is a 6th-century illuminated manuscript Gospel Book written following the reconquest of the Italian peninsula by the Byzantine Empire. Also known as Codex purpureus Rossanensis due to the reddish-purple appearance of its pages, the codex is one of the oldest surviving illuminated manuscripts of the New Testament. The manuscript is famous for its prefatory cycle of miniatures of subjects from the Life of Christ, arranged in two tiers on the page, sometimes with small Old Testament prophet portraits below, prefiguring and pointing up to events described in the New Testament scene above.

Rossano is a town and frazione of Corigliano-Rossano in the province of Cosenza, Calabria, southern Italy. The city is situated on an eminence c. three kilometres (1.9 mi) from the Gulf of Taranto. The town is known for its marble and alabaster quarries.