The trade route from the Varangians to the Greeks was a medieval trade route that connected Scandinavia, Kievan Rus' and the Eastern Roman Empire. The route allowed merchants along its length to establish a direct prosperous trade with the Empire, and prompted some of them to settle in the territories of present-day Belarus, Russia and Ukraine. The majority of the route comprised a long-distance waterway, including the Baltic Sea, several rivers flowing into the Baltic Sea, and rivers of the Dnieper river system, with portages on the drainage divides. An alternative route was along the Dniester river with stops on the western shore of Black Sea. These more specific sub-routes are sometimes referred to as the Dnieper trade route and Dniester trade route, respectively.

Kievan Rus', also known as Kyivan Rus', was a state and later an amalgam of principalities in Eastern and Northern Europe from the late 9th to the mid-13th century. The name was coined by Russian historians in the 19th century. Encompassing a variety of polities and peoples, including East Slavic, Norse, and Finnic, it was ruled by the Rurik dynasty, founded by the Varangian prince Rurik. The modern nations of Belarus, Russia, and Ukraine all claim Kievan Rus' as their cultural ancestor, with Belarus and Russia deriving their names from it, and the name Kievan Rus' derived from what is now the capital of Ukraine. At its greatest extent in the mid-11th century, Kievan Rus' stretched from the White Sea in the north to the Black Sea in the south and from the headwaters of the Vistula in the west to the Taman Peninsula in the east, uniting the East Slavic tribes.