The Royal College of Science for Ireland (RCScI) was an institute for higher education in Dublin which existed from 1867 to 1926, specialising in physical sciences and applied science. It was originally based on St. Stephen's Green, moving in 1911 to a purpose-built "Royal College of Science" building on Merrion Street, now known as Government Buildings. In 1926 it was absorbed into University College Dublin (UCD) as the faculty of Science and Engineering.

Merrion Street is a major Georgian street on the southside of Dublin, Ireland, which runs along one side of Merrion Square. It is divided into Merrion Street Lower, Merrion Square West and Merrion Street Upper. It holds one entrance to the seat of the Irish Parliament, the Oireachtas, major government offices and two major cultural institutions.