The Royal Hobart Hospital is a public hospital in the Hobart CBD, Tasmania, Australia. The hospital also functions as a teaching hospital in co-operation with the University of Tasmania. The hospital's research facilities are known as the Royal Hobart Hospital Research Foundation. Also close to the hospital site is the Menzies Research Institute.

Hobart City Centre is a suburb surrounded by metropolitan Hobart, which comprises the original settlement, the central business district, and other built-up areas. It is the oldest part of Hobart and includes many of the city's important institutions and landmarks, such as Parliament, the Supreme Court, Franklin Square, the Elizabeth Street Mall, the Royal Hobart Hospital, the Theatre Royal, Odeon Theatre, State Library, the NAB Building, the Museum, and the Cenotaph. The city centre is located in the local government areas of the City of Hobart.