The Royal Prince Alfred Hospital is a large teaching hospital in Sydney, Australia, located on Missenden Road in Camperdown. It is a teaching hospital of the Central Clinical School of the Sydney Medical School at the University of Sydney and is situated in proximity to the Blackburn Building of the university's main campus. RPAH is the largest hospital in the Sydney Local Health District, with approximately 1200 beds. Following a $350 million redevelopment, the perinatal hospital King George V Memorial Hospital has been incorporated into it.

A teaching hospital is a hospital or medical center that provides medical education and training to future and current health professionals. Teaching hospitals are almost always affiliated with one or more universities and are often co-located with medical schools.