"Run the Show" is a song by American singer Kat DeLuna from her debut studio album 9 Lives. It was released as the second worldwide single off her debut album. While the album version features vocals from Shaka Dee, the single version features a new rap from Busta Rhymes. It was officially sent to big radio stations on January 15, 2008. The Spanish version features reggaeton artist Don Omar.

Kathleen Emperatriz DeLuna is an American singer.