Rush University Medical Center (Rush) is an academic medical center in the Illinois Medical District neighborhood of Chicago, Illinois. It is the flagship hospital for the Rush University System for Health, which includes Rush Oak Park Hospital and Rush Copley Medical Center, and serves as the primary teaching hospital in affiliation with Rush University.

Rush Medical College is the medical school of Rush University, located in the Illinois Medical District, about 3 km west of the Loop in Chicago. Offering a full-time Doctor of Medicine program, the school was chartered in 1837, and today is affiliated primarily with Rush University Medical Center, and nearby John H. Stroger Jr. Hospital of Cook County. In 2021, Rush Medical College was ranked 64th among research institutions in the U.S. by U.S. News & World Report.