Russian Mission is a city in Kusilvak Census Area, Alaska. It was the location of a fur trading post of the Russian-American Company in 1842. After the sale of Russian-American possessions to the United States in 1867, it was officially named Russian Mission in the early 1900s. The sale of alcohol is prohibited. At the 2020 census the population was 421, up from 312 in 2010.

Central Alaskan Yupʼik is one of the languages of the Yupik family, in turn a member of the Eskimo–Aleut language group, spoken in western and southwestern Alaska. Both in ethnic population and in number of speakers, the Central Alaskan Yupik people form the largest group among Alaska Natives. As of 2010 Yupʼik was, after Navajo, the second most spoken aboriginal language in the United States. Yupʼik should not be confused with the related language Central Siberian Yupik spoken in Chukotka and St. Lawrence Island, nor Naukan Yupik likewise spoken in Chukotka.