Rutherglen High School is a non-denominational, co-educational secondary school in Cambuslang, South Lanarkshire, Scotland, for pupils with additional support needs.

Cambuslang is a town on the south-eastern outskirts of Greater Glasgow, Scotland. With approximately 30,000 residents, it is the 27th largest town in Scotland by population, although, never having had a town hall, it may also be considered the largest village in Scotland. It is within the local authority area of South Lanarkshire and directly borders the town of Rutherglen to the west. Historically, it was a large civil parish incorporating the nearby hamlets of Newton, Flemington, Westburn and Halfway.