The Georgian S6 route, also known as Ponichala–Marneuli–Guguti, is a "road of international importance" within the Georgian road network and runs from Ponichala in Tbilisi via Marneuli and Bolnisi to

Bolnisi is a municipality in Georgia's southern region of Kvemo Kartli, covering an area of 804 km2. As of 2021, it had a population of 56,036 people. The city of Bolnisi is its administrative centre.