SM UB-16 was a German Type UB I submarine or U-boat in the German Imperial Navy during World War I. The submarine was sunk by a British submarine in May 1918.

The Type UB I submarine was a class of small coastal submarines (U-boats) built in Germany at the beginning of the First World War. Twenty boats were constructed, most of which went into service with the German Imperial Navy Boats of this design were also operated by the Austro-Hungarian Navy and the Bulgarian Navy. In the Austro-Hungarian Navy, it was called the U-10 class.