STAT protein
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Members of the signal transducer and activator of transcription protein family are intracellular transcription factors that mediate many aspects of cellular immunity, proliferation, apoptosis and diff
structure of an activated dictyostelium stat in its DNA-unbound form
Structure of the amino-terminal protein interaction domain of STAT-4.
Interferon
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Interferons are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons caus
STAT protein
…function of the immune system and play a role in maintaining immune tolerance and tumor surveillance. The first two STAT proteins were identified in the interferon system. There are seven mammalian STAT family members that have been identified: STAT1, STAT2, STAT3, STAT4, STAT5 (STAT5A and STAT5B), and STAT6. STAT1…
Three vials filled with human leukocyte interferon
Sidney Pestka of Rutgers University, seen here receiving the National Medal of Technology.