STS-43, the ninth mission for Space Shuttle Atlantis, was a nine-day mission whose primary goal was launching the TDRS-E satellite (TDRS-5). The flight also tested an advanced heatpipe radiator for potential use on the then-future space station and conducted a variety of medical and materials science investigations.

Space Shuttle Atlantis is a retired Space Shuttle orbiter vehicle which belongs to NASA, the spaceflight and space exploration agency of the United States. Atlantis was manufactured by the Rockwell International company in Southern California and was delivered to the Kennedy Space Center in Eastern Florida in April 1985. Atlantis is also the fourth operational and the second-to-last Space Shuttle built. Its maiden flight was STS-51-J made from October 3 to 7, 1985.