STS-93 in 1999 marked the 95th launch of the Space Shuttle, the 26th launch of Columbia, and the 21st night launch of a Space Shuttle. Eileen Collins became the first female shuttle Commander on this flight. Its primary payload was the Chandra X-ray Observatory.

Space Shuttle abort modes were procedures by which the nominal launch of the NASA Space Shuttle could be terminated. A pad abort occurred after ignition of the shuttle's main engines but prior to liftoff. An abort during ascent that would result in the orbiter returning to a runway or to an orbit lower than planned was called an "intact abort", while an abort in which the orbiter would be unable to reach a runway, or any abort involving the failure of more than one main engine, was called a "contingency abort". Crew bailout was still possible in some situations in which the orbiter could not land on a runway.