Occupying a peninsula between the Sakonnet River and Rhode Island Sound, the 242-acre (0.98 km2) Sachuest Point National Wildlife Refuge is a very popular site for the over 65,000 annual visitors each year. It is located in the southeasternmost part of the Town of Middletown.

Middletown is a town in Newport County, Rhode Island, United States. The population was 17,075 at the 2020 census. It lies to the south of Portsmouth and to the north of Newport on Aquidneck Island, hence the name "Middletown."