The Sacramento River is the principal river of Northern California in the United States and is the largest river in California. Rising in the Klamath Mountains, the river flows south for 400 miles (640 km) before reaching the Sacramento–San Joaquin River Delta and San Francisco Bay. The river drains about 26,500 square miles (69,000 km2) in 19 California counties, mostly within the fertile agricultural region bounded by the Coast Ranges and Sierra Nevada known as the Sacramento Valley, but also extending as far as the volcanic plateaus of Northeastern California. Historically, its watershed has reached as far north as south-central Oregon where the now, primarily, endorheic (closed) Goose Lake rarely experiences southerly outflow into the Pit River, the most northerly tributary of the Sacramento.

The Klamath Mountains are a rugged and lightly-populated mountain range in northwestern California and southwestern Oregon in the western United States. As a mountain system within both the greater Pacific Coast Ranges and the California Coast Ranges, the Klamath Mountains have a varied geology, with substantial areas of serpentinite and marble, and a climate characterized by moderately cold winters with very heavy snowfall and warm, very dry summers with limited rainfall, especially in the south. As a consequence of the geology and soil types, the mountains harbor several endemic or near-endemic trees, forming one of the largest collections of conifers in the world. The mountains are also home to a diverse array of fish and animal species, including black bears, large cats, owls, eagles, and several species of Pacific salmon. Millions of acres in the mountains are managed by the United States Forest Service. The northernmost and largest sub-range of the Klamath Mountains are the Siskiyou Mountains.