Saddar Town, lies in the south part of the city that formed much of the historic colonial core of Karachi.

Lyari Town is named after the historic locality of Lyari. Lyari Town was the smallest borough by area, but also the most densely populated one. Lyari Town was formed in 2001 as part of The Local Government Ordinance 2001, and was subdivided into 11 Union councils. The town system was disbanded in 2011, and Lyari Town was re-organized as part of Karachi South in 2015.