Saighton Grange originated as a monastic grange. It was later converted into a country house and, as of 2013, the building is used as a school. It is located in Saighton, Cheshire, England. The only surviving part of the monastic grange is the gatehouse, which is recorded in the National Heritage List for England as a designated Grade I listed building, and is one of only two surviving monastic manorial buildings in Cheshire, the other being Ince Manor. The rest of the building is listed at Grade II, as is its chapel.

Saighton is a village and former civil parish, now in the parish of Aldford and Saighton, in the unitary authority area of Cheshire West and Chester and the ceremonial county of Cheshire, England, a few miles south of Chester. The 2011 Census recorded a population for the parish of 202. Much of the surrounding land is owned by the Duke of Westminster.