Saint Joseph Academy is the only all-female Catholic high school located in Cleveland, Ohio. It is located in the Roman Catholic Diocese of Cleveland. An Associate of the Congregation of St. Joseph serves as Vice President of Mission, and seven faculty and staff members are Associates of the Congregation of St. Joseph.

Patricia Jean Donahue, known as Patty Donahue, was the lead singer of the 1980s new wave group The Waitresses. She is best known for the band’s singles "I Know What Boys Like" and "Christmas Wrapping".