Saint Joseph Academy is the only all-female Catholic high school located in Cleveland, Ohio. It is located in the Roman Catholic Diocese of Cleveland. An Associate of the Congregation of St. Joseph serves as Vice President of Mission, and seven faculty and staff members are Associates of the Congregation of St. Joseph.

The Diocese of Cleveland is a Latin Church ecclesiastical territory, or diocese, of the Catholic Church in northeastern Ohio in the United States. As of September 2020, the bishop is Edward Malesic. The Cathedral of St. John the Evangelist, located in Cleveland, is the mother church of the diocese.